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Recombinant NGFR 抗体

The 兔 单克隆 anti-NGFR antibody (Clone NGFR-1997R) (ABIN5707549) specifically detects NGFR in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN5707549
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant NGFR 抗体 (ABIN5707549)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This NGFR antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

NGFR-1997R
  • 原理

    Recombinant p75NTR Antibody / NGFR

    交叉反应 (详细)

    Not suitable for mouse

    纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for the recombinant p75NTR antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant p75NTR antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant p75NTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    p75NTR

    背景

    This antibody is specific for a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or p75 Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR/p75NTR is a reliable marker for desmoplastic and neurotropic melanomas. It is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR/p75NTR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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