ABI1 抗体 (C-Term)
Quick Overview for ABI1 抗体 (C-Term) (ABIN5706835)
抗原
See all ABI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 600-401-gt5
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Supplier
- Rockland
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原理
- Abi1 Antibody
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交叉反应 (详细)
- Anti-Abi1 is directed against mouse Abi1.
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产品特性
- Synonyms: rabbit anti-Abi1 Antibody, Abi 1, Abi-1, Abl Interactor 1, Eps8 SH3 Domain-Binding Protein, Abl-Binding Protein, Abelson Interactor 1, E3B1, Spectrin SH3 Domain Binding Protein 1, Nap1-binding protein, SSH3BP1
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纯化方法
- This product is an affinity purified antibody produced by immunoaffinity chromatography using peptide coupled to agarose beads.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to near c-terminal of the mouse Abi-1 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 65 kDa in size corresponding to Abi1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1.0 μg/mL
ELISA Dilution: 5.0 μg/mL
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- ABI1 (Abl-Interactor 1 (ABI1))
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别名
- Abi1
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背景
- Background: Anti-Abi1 Antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Abi1 gene has been suggested to have a role in inhibiting cell growth and encodes an adaptor protein in the Abelson-interactor family. The protein is involved in signal transduction, actin regulation and cytoskeletal remodeling. Studies suggest that Abi1 is a member of the WAVE complex and a dysfunctional complex may allow for the progression of prostate cancer. Anti-Abi1 is ideal for researchers interested in melanoma, colon and breast cancer and other cancer antibody research.
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基因ID
- 11308
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NCBI登录号
- NP_001070658
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UniProt
- Q8CBW3
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途径
- RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
抗原
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