PEX5 抗体
Quick Overview for PEX5 抗体 (ABIN5704976)
抗原
See all PEX5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
免疫原
- peroxisomal biogenesis factor 5
-
亚型
- IgG
-
-
-
-
应用备注
- WB : 1:500-1:5000 IP : 1:200-1:2000 IHC : 1:100-1:400 IF : 1:50-1:500
-
说明
-
human brain tissue were subjected to SDS PAGE followed by western blot with FNab06331(PEX5 antibody) at dilution of 1:500
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
有效期
- 12 months
-
-
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
-
别名
- PEX5
-
背景
- Synonyms:FLJ50634, FLJ50721, FLJ51948, Peroxin 5, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1 Background:The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
-
分子量
- 70 kDa
-
基因ID
- 5830
-
UniProt
- P50542
-
途径
- Monocarboxylic Acid Catabolic Process
抗原
-