RFC4 抗体
Quick Overview for RFC4 抗体 (ABIN5704273)
抗原
See all RFC4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RFC4 antibody
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免疫原
- replication factor C (activator 1) 4, 37kDa
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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别名
- RFC4
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背景
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Synonyms: Replication factor C subunit 4|Activator 1 37 kDa subunit (A1 37 kDa subunit)|Activator 1 subunit 4|Replication factor C 37 kDa subunit (RF-C 37 kDa subunit, RFC37)|RFC4
Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
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基因ID
- 5984
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UniProt
- P35249
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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