RASGRF1 抗体
Quick Overview for RASGRF1 抗体 (ABIN5704262)
抗原
See all RASGRF1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RASGRF1 antibody
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免疫原
- Ras protein-specific guanine nucleotide-releasing factor 1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
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别名
- RASGRF1
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背景
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Synonyms: Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1)|Guanine nucleotide-releasing protein (GNRP)|Ras-specific nucleotide exchange factor CDC25|RASGRF1|CDC25|GNRP|GRF1
Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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基因ID
- 5923
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UniProt
- Q13972
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途径
- RTK signaling, Cell Division Cycle, M Phase
抗原
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