TIA1 抗体
Quick Overview for TIA1 抗体 (ABIN5704065)
抗原
See all TIA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TIA1 antibody
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免疫原
- TIA1 cytotoxic granule-associated RNA binding protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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别名
- TIA1
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背景
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Synonyms: Cytotoxic granule associated RNA binding protein TIA1|Nucleolysin TIA-1 isoform p40|RNA-binding protein TIA-1|T-cell-restricted intracellular antigen-1 (TIA-1)|p40-TIA-1|TIA1
Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
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基因ID
- 7072
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UniProt
- P31483
抗原
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