MMP14 抗体 (AA 100-200)
Quick Overview for MMP14 抗体 (AA 100-200) (ABIN5703940)
抗原
See all MMP14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-200
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原理
- MMP14 antibody
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免疫原
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Immunogen sequence: 100-200aa,Extracellular domain
Immunogen: matrix metallopeptidase 14 (membrane-inserted)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
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别名
- MMP14
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背景
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Synonyms: Matrix metalloproteinase-14 (MMP-14)|MMP-X1|Membrane-type matrix metalloproteinase 1 (MT-MMP 1, MTMMP1)|Membrane-type-1 matrix metalloproteinase (MT1-MMP, MT1MMP)|MMP14
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
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基因ID
- 4323
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UniProt
- P50281
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途径
- Autophagy
抗原
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