BTK 抗体
Quick Overview for BTK 抗体 (ABIN5702372)
抗原
See all BTK 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BTK antibody
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免疫原
- Bruton agammaglobulinemia tyrosine kinase
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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别名
- BTK
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背景
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Synonyms: Tyrosine-protein kinase BTK|Agammaglobulinemia tyrosine kinase (ATK)|B-cell progenitor kinase (BPK)|Bruton tyrosine kinase|BTK|AGMX1|ATK|BPK
Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 70-76 kDa
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基因ID
- 695
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UniProt
- Q06187
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途径
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
抗原
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