PARP1 抗体
Quick Overview for PARP1 抗体 (ABIN5702300)
抗原
See all PARP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PARP1 antibody
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免疫原
- poly (ADP-ribose) polymerase 1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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别名
- PARP1
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背景
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Synonyms: Poly [ADP-ribose] polymerase 1 (PARP-1)|ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1)|DNA ADP-ribosyltransferase PARP1|NAD(+) ADP-ribosyltransferase 1 (ADPRT 1)|Poly[ADP-ribose] synthase 1|Protein poly-ADP-ribosyltransferase PARP1|Poly [ADP-ribose] polymerase 1, processed C-terminus Alternative names: Poly [ADP-ribose] polymerase 1, 89- kDa form|Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) Alternative names: Poly [ADP-ribose] polymerase 1, 24- kDa form|Poly [ADP-ribose] polymerase 1, 28- kDa form|PARP1|ADPRT|PPOL
Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
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基因ID
- 142
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UniProt
- P09874
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途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
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