电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DDB1 抗体

This anti-DDB1 antibody is a 兔 多克隆 antibody detecting DDB1 in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5699738
发货至: 中国

Quick Overview for DDB1 抗体 (ABIN5699738)

抗原

See all DDB1 抗体
DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

适用

  • 45
  • 23
  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 37
  • 7
  • 1

克隆类型

  • 35
  • 10
多克隆

标记

  • 34
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DDB1 antibody is un-conjugated

应用范围

  • 30
  • 15
  • 14
  • 14
  • 10
  • 10
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 免疫原

    damage-specific DNA binding protein 1, 127kDa

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab02284(DDB1 antibody) at dilution of 1:500

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

    别名

    DDB1

    背景

    Synonyms:DDB p127 subunit, DDB1, DDBA, DNA damage binding protein 1, DNA damage binding protein a, HBV X associated protein 1, UV damaged DNA binding factor, UV DDB 1, UV Background:The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.

    分子量

    127 kDa

    基因ID

    1642

    UniProt

    Q16531

    途径

    DNA Damage Repair
You are here:
Chat with us!