DDB1 抗体
Quick Overview for DDB1 抗体 (ABIN5699738)
抗原
See all DDB1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DDB1 antibody
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免疫原
- damage-specific DNA binding protein 1, 127kDa
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亚型
- IgG
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anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibody
Verified DDB1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibodyKO Validated DDB1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) antibodyDDB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibodyDDB1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) antibodyDDB1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 1011-1140) antibodyDDB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 1044-1140) antibodyDDB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) antibodyDDB1 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibodyDDB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 741-943) antibodyDDB1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab02284(DDB1 antibody) at dilution of 1:500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))
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别名
- DDB1
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背景
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Synonyms: DNA damage-binding protein 1|DDB p127 subunit|DNA damage-binding protein a (DDBa)|Damage-specific DNA-binding protein 1|HBV X-associated protein 1 (XAP-1)|UV-damaged DNA-binding factor|UV-damaged DNA-binding protein 1 (UV-DDB 1)|XPE-binding factor (XPE-BF)|Xeroderma pigmentosum group E-complementing protein (XPCe)|DDB1|XAP1
Background: The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.
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分子量
- 127 kDa
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基因ID
- 1642
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UniProt
- Q16531
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途径
- DNA Damage Repair
抗原
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