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SSRP1 抗体

This anti-SSRP1 antibody is a 兔 多克隆 antibody detecting SSRP1 in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5699682
发货至: 中国

Quick Overview for SSRP1 抗体 (ABIN5699682)

抗原

See all SSRP1 抗体
SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

适用

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人, 小鼠, 大鼠

宿主

  • 55
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克隆类型

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多克隆

标记

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This SSRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 免疫原

    structure specific recognition protein 1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab08250(SSRP1 antibody) at dilution of 1:500

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

    别名

    SSRP1

    背景

    Synonyms:FACT80 Background:The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

    基因ID

    6749

    UniProt

    Q08945

    途径

    Chromatin Binding
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