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SSRP1 抗体

The 兔 多克隆 anti-SSRP1 antibody (ABIN5699682) specifically detects SSRP1 in WB, IHC, ELISA 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5699682
发货至: 中国
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Quick Overview for SSRP1 抗体 (ABIN5699682)

抗原

See all SSRP1 抗体
SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

适用

  • 58
  • 19
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  • 1
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 4

克隆类型

  • 53
  • 5
多克隆

标记

  • 36
  • 3
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  • 1
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This SSRP1 antibody is un-conjugated

应用范围

  • 40
  • 15
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 原理

    SSRP1 antibody

    免疫原

    structure specific recognition protein 1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab08250(SSRP1 antibody) at dilution of 1:500

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

    别名

    SSRP1

    背景

    Synonyms: FACT complex subunit SSRP1|Chromatin-specific transcription elongation factor 80 kDa subunit|Facilitates chromatin transcription complex 80 kDa subunit (FACT 80 kDa subunit, FACTp80)|Facilitates chromatin transcription complex subunit SSRP1|Recombination signal sequence recognition protein 1|Structure-specific recognition protein 1 (hSSRP1)|T160|SSRP1|FACT80

    Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

    基因ID

    6749

    UniProt

    Q08945

    途径

    Chromatin Binding
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