MYLK 抗体
Quick Overview for MYLK 抗体 (ABIN5699678)
抗原
See all MYLK 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MYLK antibody
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免疫原
- myosin light chain kinase
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MYLK (Myosin Light Chain Kinase (MYLK))
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别名
- MYLK
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背景
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Synonyms: Myosin light chain kinase, smooth muscle (MLCK, smMLCK)|Kinase-related protein (KRP)|Telokin|Myosin light chain kinase, smooth muscle, deglutamylated form|MYLK|MLCK|MLCK1|MYLK1
Background: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.
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分子量
- 135 kDa
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基因ID
- 4638
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UniProt
- Q15746
抗原
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