CDK6 抗体
Quick Overview for CDK6 抗体 (ABIN5699231)
抗原
See all CDK6 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- cyclin-dependent kinase 6
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亚型
- IgG
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应用备注
- WB : 1:200-1:2000 IP : 1:200-1:1000 IHC : 1:20-1:200 IF : 1:50-1:500
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说明
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01561(CDK6 antibody) at dilution of 1:500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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别名
- CDK6
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背景
- Synonyms:CDKN6 Background:The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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分子量
- 37-40 kDa
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基因ID
- 1021
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UniProt
- Q00534
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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