RAD18 抗体
Quick Overview for RAD18 抗体 (ABIN5698234)
抗原
See all RAD18 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RAD18 antibody
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免疫原
- RAD18 homolog
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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别名
- RAD18
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背景
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Synonyms: E3 ubiquitin-protein ligase RAD18|Postreplication repair protein RAD18 (hHR18, hRAD18)|RING finger protein 73|RING-type E3 ubiquitin transferase RAD18|RAD18|RNF73
Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
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基因ID
- 56852
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UniProt
- Q9NS91
抗原
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