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BIRC3 抗体 (Internal Region)

BIRC3 适用: 人, 大鼠 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN569625
发货至: 中国
  • 抗原 See all BIRC3 抗体
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    抗原表位
    • 15
    • 12
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 65
    • 23
    • 6
    • 1
    人, 大鼠
    宿主
    • 60
    • 5
    • 2
    山羊
    克隆类型
    • 62
    • 5
    多克隆
    标记
    • 35
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIRC3 antibody is un-conjugated
    应用范围
    • 55
    • 34
    • 26
    • 17
    • 13
    • 13
    • 11
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-SVNNLEATSQ P
    特异性
    Recognizes BIRC3.
    交叉反应 (详细)
    Species reactivity (expected):Human.
    Species reactivity (tested):Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_001156.1. Genename: BIRC3
    Top Product
    Discover our top product BIRC3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Reported variants represent identical protein: NP_892007.1, NP_001156.1.
    浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    别名
    IAP1 / BIRC3 (BIRC3 产品)
    别名
    AIP1 antibody, API2 antibody, CIAP2 antibody, HAIP1 antibody, HIAP1 antibody, MALT2 antibody, MIHC antibody, RNF49 antibody, c-IAP2 antibody, Api1 antibody, Api2 antibody, IAP1 antibody, IAP2 antibody, MIHB antibody, Birc2 antibody, HIAP2 antibody, MIAP1 antibody, MIAP2 antibody, cIAP1 antibody, cIAP2 antibody, cIAP-1 antibody, cIAP-2 antibody, AW107670 antibody, BIRC2 antibody, baculoviral IAP repeat containing 3 antibody, baculoviral IAP repeat-containing 3 antibody, baculoviral IAP repeat-containing protein 3 antibody, inhibitor of apoptosis protein-2 antibody, BIRC3 antibody, Birc3 antibody, LOC100399118 antibody, OpmnVgp074 antibody
    背景
    Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.Synonyms: API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing protein 3, C-IAP2, HIAP-1, IAP homolog C, Inhibitor of apoptosis protein 1, MIHC, RING finger protein 49, RNF49, TNFR2-TRAF-signaling complex protein 1, cIAP2
    基因ID
    330
    NCBI登录号
    NP_001156
    UniProt
    Q13489
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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