BIRC3 抗体 (Internal Region)
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北京 101111
Quick Overview for BIRC3 抗体 (Internal Region) (ABIN569625)
抗原
See all BIRC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-SVNNLEATSQ P
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特异性
- Recognizes BIRC3.
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交叉反应 （详细）
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Species reactivity (expected):Human.
Species reactivity (tested):Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_001156.1. Genename: BIRC3
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anti-Baculoviral IAP Repeat Containing 3 (BIRC3) antibody
BIRC3 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-180) antibodyBIRC3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 59-88), (N-Term) antibodyBIRC3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB34025 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131), (N-Term) antibodyBIRC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2213 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (Internal Region) antibodyVerified BIRC3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 255-529) antibodyBIRC3 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 76-245) antibodyBIRC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) antibodyBIRC3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB8125 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Reported variants represent identical protein: NP_892007.1, NP_001156.1.
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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别名
- IAP1 / BIRC3
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背景
- Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.Synonyms: API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing protein 3, C-IAP2, HIAP-1, IAP homolog C, Inhibitor of apoptosis protein 1, MIHC, RING finger protein 49, RNF49, TNFR2-TRAF-signaling complex protein 1, cIAP2
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基因ID
- 330
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NCBI登录号
- NP_001156
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UniProt
- Q13489
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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