EPH Receptor A2 抗体 (AA 851-970)
Quick Overview for EPH Receptor A2 抗体 (AA 851-970) (ABIN5693218)
抗原
See all EPH Receptor A2 (EPHA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 851-970
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原理
- Anti-Eph receptor A2/EPHA2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Eph receptor A2/EPHA2 Antibody Picoband® (ABIN5693218). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Eph receptor A2 recombinant protein (Position: M851-N970).
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亚型
- IgG
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anti-EPH Receptor A2 (EPHA2) (AA 30-60), (N-Term) antibody
EPHA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01579 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 901-976) antibodyEPHA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 204-326) antibodyEPHA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 适用: 人 FACS, IF, cELISA 宿主: 小鼠 Monoclonal Kalpha-5H5 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 30-60) antibodyEPHA2 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 333-347), (Extracellular) antibodyEPHA2 适用: 人 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 847-976) antibodyEPHA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1B3C7 unconjugated
anti-EPH Receptor A2 (EPHA2) (pTyr594) antibodyEPHA2 适用: 人 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 627-976) antibodyEPHA2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Ganju, P., Shigemoto, K., Brennan, J., Entwistle, A., Reith, A. D. The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development. Oncogene 9: 1613-1624, 1994. 2. Jun, G., Guo, H., Klein, B. E. K., Klein, R., Wang, J. J., Mitchell, P., Miao, H., Lee, K. E., Joshi, T., Buck, M., Chugha, P., Bardenstein, D., and 9 others. EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet. 5: e1000584, 2009. 3. Khounlotham, M., Subbian, S., Smith, R., III, Cirillo, S. L. G., Cirillo, J. D. Mycobacterium tuberculosis interferes with the response to infection by inducing the host EphA2 receptor. J. Infect. Dis. 199: 1797-1806, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- EPH Receptor A2 (EPHA2)
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别名
- EPHA2
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背景
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Synonyms: Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA2, ECK
Tissue Specificity: Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary.
Background: EPHA2 (ephrin type-A receptor 2) also known as ECK, is a protein that in humans is encoded by the EPHA2 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. By somatic cell hybrid analysis and fluorescence in situ hybridization, the EPHA2 gene is mapped to chromosome 1p36.1. EPHA2 was readily detectable in human lens fiber cells using immunoblot and immunohistochemistry. EGFR and EPHA2 mediated HCV entry by regulating CD81 -claudin-1 (CLDN1) coreceptor associations and viral glycoprotein-dependent membrane fusion.
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分子量
- 125 kDa
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基因ID
- 1969
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UniProt
- P29317
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途径
- RTK signaling
抗原
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