Caspase 4 抗体 (AA 111-194)
Quick Overview for Caspase 4 抗体 (AA 111-194) (ABIN5693193)
抗原
See all Caspase 4 (CASP4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 111-194
-
原理
- Anti-Caspase 4/CASP4 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Caspase 4/CASP4 Antibody Picoband® (ABIN5693193). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
免疫原
- E. coli-derived human Caspase 4 recombinant protein (Position: H111-R194).
-
亚型
- IgG
-
-
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 1-377) antibody
CASP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G7 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 290-377) antibodyCASP4 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 82-226) antibodyCASP4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibodyCASP4 适用: 小鼠, 大鼠 WB, ELISA, IP, FACS 宿主: 大鼠 Monoclonal 8A5 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Cleaved-Gln81) antibodyCASP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 78-265) antibodyCASP4 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 81-270) antibodyCASP4 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Internal Region) antibodyVerified CASP4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 104-124) antibodyCASP4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (N-Term) antibodyCASP4 适用: 人, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
Immunofluorescence, 2 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Kajiwara, Y., Akram, A., Katsel, P., Haroutunian, V., Schmeidler, J., Beecham, G., Haines, J. L., Pericak-Vance, M. A., Buxbaum, J. D.FE65 binds teashirt, inhibiting expression of primate-specific caspase-4. PLoS One 4:e5071, 2009. 2. Kamens, J., Paskind, M., Hugunin, M., Talanian, R. V., Allen, H., Banach, D., Bump, N., Hackett, M., Johnston, C. G., Li, P., Mankovich, J. A., Terranova, M., Ghayur, T.Identification and characterization of ICH-2, a novel member of the interleukin-1-beta-converting enzyme family of cysteine proteases.J. Biol. Chem. 270: 15250-15256, 1995. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
-
别名
- CASP4
-
背景
-
Synonyms: Caspase-4, CASP-4
Tissue Specificity: Widely expressed, including in keratinocytes and colonic and small intestinal epithelial cells (at protein level). Not detected in brain.
Background: Caspase 4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. The Caspase 4 gene is mapped to a P1 clone containing the ICE gene, which is located at chromosome 11q22.2-q22.3. It contains 8 coding exons. The function of caspase 4 is not fully known, but it is believed to be an inflammatory caspase, along with caspase 1, caspase 5 (and the murine homolog caspase 11), with a role in the immune system.
-
分子量
- 48 kDa
-
基因ID
- 837
-
UniProt
- P49662
-
途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
-
