BIRC2 抗体 (AA 320-570)
Quick Overview for BIRC2 抗体 (AA 320-570) (ABIN5693185)
抗原
See all BIRC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 320-570
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原理
- Anti-cIAP1/BIRC2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-cIAP1/BIRC2 Antibody Picoband® (ABIN5693185). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human cIAP1 recombinant protein (Position: D320-T570).
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亚型
- IgG
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anti-Baculoviral IAP Repeat Containing 2 (BIRC2) (AA 1-300) antibody
BIRC2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 2 (BIRC2) (C-Term) antibodyBIRC2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 2 (BIRC2) (AA 1-618) antibodyBIRC2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 2 (BIRC2) antibodyBIRC2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Baculoviral IAP Repeat Containing 2 (BIRC2) (AA 344-593) antibodyBIRC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 2 (BIRC2) (AA 148-298) antibodyBIRC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 2 (BIRC2) (C-Term) antibodyBIRC2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bertrand, M. J. M., Doiron, K., Labbe, K., Korneluk, R. G., Barker, P. A., Saleh, M. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity 30: 789-801, 2009. 2. Dai, Z., Zhu, W.-G., Morrison, C. D., Brena, R. M., Smiraglia, D. J., Raval, A., Wu, Y.-Z., Rush, L. J., Ross, P., Molina, J. R., Otterson, G. A., Plass, C. A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes. Hum. Molec. Genet. 12: 791-801, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
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别名
- BIRC2
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背景
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Synonyms: Baculoviral IAP repeat-containing protein 2
Tissue Specificity: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Background: Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 70 kDa
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基因ID
- 329
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UniProt
- Q13490
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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