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BIRC2 抗体 (C-Term)

The 兔 多克隆 anti-BIRC2 antibody (ABIN499623) specifically detects BIRC2 in WB, IHC (p) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN499623
发货至: 中国
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Quick Overview for BIRC2 抗体 (C-Term) (ABIN499623)

抗原

See all BIRC2 抗体
BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

适用

  • 68
  • 8
  • 6
人, 小鼠

宿主

  • 64
  • 4

克隆类型

  • 34
  • 34
多克隆

标记

  • 26
  • 9
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
This BIRC2 antibody is un-conjugated

应用范围

  • 62
  • 40
  • 27
  • 25
  • 20
  • 13
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    特异性

    C-IAP antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 c-IAP antibody detects both c-IAP1 and c-IAP2.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human cIAP (C-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: cIAP antibody can be used for the detection of c-IAP at 1 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

    别名

    IAP2 / BIRC2

    背景

    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases (1 for review). The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspasesSynonyms: API1, Baculoviral IAP repeat-containing protein 2, C-IAP1, HIAP-2, HIAP2, IAP homolog B, Inhibitor of apoptosis protein 2, MIHB, RING finger protein 48, RNF48, TNFR2-TRAF-signaling complex protein 2, cIAP1

    基因ID

    329

    NCBI登录号

    NP_001157

    UniProt

    Q13490

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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