PAI1 抗体 (AA 24-240)
(1 reference)Quick Overview for PAI1 抗体 (AA 24-240) (ABIN5693180)
抗原
See all PAI1 (SERPINE1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-240
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原理
- Anti-PAI1/Serpine1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PAI1/Serpine1 Antibody Picoband® (ABIN5693180). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived rat PAI1 recombinant protein (Position: S24-D240).
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亚型
- IgG
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anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibody
SERPINE1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1D5 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (Internal Region) antibodyVerified SERPINE1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 86-185) antibodySERPINE1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 6F3 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 141-389) antibodySERPINE1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-398) antibodySERPINE1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Boncela J, Papiewska I, Fijalkowska I, Walkowiak B, Cierniewski CS (September 2001). "Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type 1 and stabilizes its inhibitory activity". The Journal of Biological Chemistry. 276 (38): 35305-11. 2. Elokdah H, Abou-Gharbia M, Hennan JK, McFarlane G, Mugford CP, Krishnamurthy G, Crandall DL (July 2004). "Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: design, synthesis, and preclinical characterization". Journal of Medicinal Chemistry. 47 (14): 3491-4. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).
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: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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别名
- Serpine1
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背景
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Synonyms: Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, Serpine1, Pai1, Planh1
Tissue Specificity: Ubiquitous.
Background: Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitoror serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 45-50 kDa
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基因ID
- 5054
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UniProt
- P20961
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途径
- p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
抗原
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