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Cytochrome C 抗体 (AA 2-105) (DyLight 488)

This anti-Cytochrome C antibody is a 小鼠 单克隆 antibody detecting Cytochrome C in FACS. Suitable for 人.
产品编号 ABIN5693009
发货至: 中国

Quick Overview for Cytochrome C 抗体 (AA 2-105) (DyLight 488) (ABIN5693009)

抗原

See all Cytochrome C (CYCS) 抗体
Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

适用

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宿主

  • 112
  • 107
  • 5
  • 1
小鼠

克隆类型

  • 137
  • 87
  • 1
单克隆

标记

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This Cytochrome C antibody is conjugated to DyLight 488

应用范围

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Flow Cytometry (FACS)

克隆位点

15F10
  • 抗原表位

    • 43
    • 16
    • 10
    • 5
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    AA 2-105

    原理

    Anti-Human Cytochrome C DyLight® 488 conjugated CYCS Antibody(monoclonal, 15F10)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Human Cytochrome C DyLight® 488 conjugated CYCS Antibody (monoclonal, 15F10) -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

    免疫原

    E.coli-derived human Cytochrome C recombinant protein (Position: G2-E105). Human Cytochrome C shares 91% amino acid (aa) sequence identity with both mouse and rat Cytochrome C.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. García-Heredia JM, et al. Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome. FEBS Lett, 2012 Jan 20. 2. Rajagopal BS, et al. The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant. Biochem J, 2013 Dec 15. 3. Simon M, et al. Versatility of non-native forms of human cytochrome c: pH and micellar concentration dependence. J Biol Inorg Chem, 2013 Jan.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
  • 抗原

    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

    别名

    CYCS

    背景

    Synonyms: Cytochrome c, CYCS, CYC

    Background: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

    分子量

    39 kDa

    基因ID

    54205

    UniProt

    P99999

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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