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ADAM10 抗体 (AA 214-325)

Name: ADAM10 抗体 (AA 214-325)
SKU: ABIN5692975
Availability: OutOfStock

ADAM10 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of ADAM10 using anti-ADAM10 antibody . (ADAM10 抗体 (AA 214-325))

1 image

(1 reference)

产品编号 ABIN5692975

发货至: 中国

Datasheet as PDF

抗原 See all ADAM10 抗体

ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
抗原表位
14

5

5

3

2

2

2

2

1

1

1

1

1

1

1
AA 214-325
适用
63

30

25

2

1

1
人, 小鼠, 大鼠
宿主
50

13

2

1
兔
Compatible Secondaries
克隆类型
42

24
多克隆
标记
31

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This ADAM10 antibody is un-conjugated
应用范围
39

17

17

12

12

11

7

6

5

5

4

2
Western Blotting (WB), ELISA

原理

Anti-ADAM10 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-ADAM10 Antibody Picoband® (ABIN5692975). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human ADAM10 recombinant protein (Position: T214-D325).

亚型

IgG

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anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 501-600) antibody
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ADAM10 适用: 人 FACS 宿主: 小鼠 Monoclonal 11G2 PE

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 214-500) antibody
ADAM10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody
ADAM10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 501-600) antibody (Biotin)
ADAM10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin

anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 501-600) antibody (AbBy Fluor® 555)
ADAM10 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555

应用备注

Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Lunn, C. A., Fan, X., Dalie, B., Miller, K., Zavodny, P. J., Narula, S. K., Lundell, D.Purification of ADAM 10 from bovine spleen as a TNFalpha convertase.FEBS Lett. 400: 333-335, 1997. 2. Wolfsberg, T. G., Primakoff, P., Myles, D. G., White, J. M.ADAM, a novel family of membrane proteins containing a disintegrin and metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions.J. Cell Biol. 131: 275-278, 1995. 3. Yamazaki, K., Mizui, Y., Tanaka, I.Radiation hybrid mapping of human ADAM10 gene to chromosome 15.Genomics 45: 457-459, 1997.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Lin, Huang, Xie, Zhou, Yang, Huang: "Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein." in: Oncotarget, Vol. 7, Issue 43, pp. 70092-70099, (2018) (PubMed).
抗原

ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

别名

ADAM10 (ADAM10 产品)

背景

Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease, CD156c, ADAM10, KUZ, MADM
Tissue Specificity: Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver.
Background: ADAM10, A Disintegrin and Metalloproteinase Domain 10, is also known as AD10. ADAM10 is a member of the ADAM family and members of this family are cell surface proteins with a unique structure possessing both potential adhesion and protease function. The ADAM10 gene is mapped to chromosome 15q21.3-q23. ADAM proteins contain an N-terminal signal sequence, followed by a prodomain, a metalloprotease-like domain, a disintegrin-like domain, a cysteine-rich region, an EGF -like repeat, a transmembrane domain, and a C-terminal cytoplasmic tail. Conversion of the membrane-bound precursor to a secreted mature protein is mediated by a protease termed TNFA convertase. ADAM10 possesses TNFA convertase activity.

分子量

72 kDa

基因ID

102

UniProt

O14672

途径

Notch Signaling, EGFR Signaling Pathway