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STAT2 抗体

This anti-STAT2 antibody is a 兔 多克隆 antibody detecting STAT2 in WB, ICC, IF 和 FACS. Suitable for 人.
产品编号 ABIN5692942
发货至: 中国

Quick Overview for STAT2 抗体 (ABIN5692942)

抗原

See all STAT2 抗体
STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

适用

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宿主

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克隆类型

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多克隆

标记

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This STAT2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Anti-STAT2 Antibody Picoband®

    序列

    FQDQLHQLYS HSLLPVDIRQ YLAVWIEDQN WQEA

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-STAT2 Antibody Picoband® (ABIN5692942). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human STAT2, which shares 73.5% and 76.5% amino acid (aa) sequence identity with mouse and rat STAT2, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells1. Banninger, G., Reich, N. C. STAT2 nuclear trafficking. J. Biol. Chem. 279: 39199-39206, 2004. 2. Bluyssen, H. A. R., Levy, D. E. Stat2 is a transcriptional activator that requires sequence-specific contacts provided by Stat1 and p48 for stable interaction with DNA. J. Biol. Chem. 272: 4600-4605, 1997. 3. Yan R, Qureshi S, Zhong Z, Wen Z, Darnell JE Jr (Apr 1995). "The genomic structure of the STAT genes: multiple exons in coincident sites in Stat1 and Stat2". Nucleic Acids Res 23 (3): 459-63.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

    别名

    STAT2

    背景

    Synonyms: Signal transducer and activator of transcription 2, p113, STAT2

    Background: Signal transducer and activator of transcription 2 (STAT2) is a protein that in humans is encoded by the STAT2 gene. The protein encoded by this gene is a member of the STAT protein family. The International Radiation Hybrid Mapping Consortium mapped the STAT2 gene to chromosome 12. STAT2 is a transcription factor critical to the signal transduction pathway of type I interferons. ISGF3 (STAT2) assembly involves p48 functioning as an adaptor protein to recruit Stat1 and Stat2 to an IFN-alpha-stimulated response element, Stat2 contributes a potent transactivation domain but is unable to ly contact DNA, while Stat1 stabilizes the heteromeric complex by contacting DNA ly.

    分子量

    113 kDa

    基因ID

    6773

    UniProt

    P52630

    途径

    JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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