NADPH Oxidase 4 抗体
(2 references)Quick Overview for NADPH Oxidase 4 抗体 (ABIN5692899)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-NADPH oxidase 4/NOX4 Antibody Picoband®
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序列
- ILNTLLDDWK PYKLRRLYFI WVCRDIQSFR WFADLL
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NADPH oxidase 4/NOX4 Antibody Picoband® (ABIN5692899). Tested in IF, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human NADPH oxidase 4, which shares 97.2% amino acid (aa) sequence identity with both mouse and rat NADPH oxidase 4.
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亚型
- IgG
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anti-NADPH Oxidase 4 (NOX4) (AA 210-310) antibody
NOX4 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3H2G11 unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 328-578) antibodyNOX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 220-392) antibodyNOX4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 81-180) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IP, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 210-424) antibodyNOX4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 561-578), (C-Term) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 124-153), (N-Term) antibodyNOX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34043 unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 124-153) antibodyNOX4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 201-300) antibodyNOX4 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 210-424) antibodyNOX4 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
1. Ago, T., Kitazono, T., Ooboshi, H., Iyama, T., Han, Y. H., Takada, J., Wakisaka, M., Ibayashi, S., Utsumi, H., Iida, M. Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase. Circulation 109: 227-233, 2004. 2. Geiszt, M., Kopp, J. B., Varnai, P., Leto, T. L. Identification of Renox, an NAD(P)H oxidase in kidney. Proc. Nat. Acad. Sci. 97: 8010-8014, 2000. 3. Shiose, A., Kuroda, J., Tsuruya, K., Hirai, M., Hirakata, H., Naito, S., Hattori, M., Sakaki Y., Sumimoto, H. A novel superoxide-producing NAD(P)H oxidase in kidney. J. Biol. Chem. 276: 1417-1423, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis." in: Antioxidants & redox signaling, (2018) (PubMed).
: "Obligatory role for GPER in cardiovascular aging and disease." in: Science signaling, Vol. 9, Issue 452, pp. ra105, (2017) (PubMed).
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: "A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis." in: Antioxidants & redox signaling, (2018) (PubMed).
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- NADPH Oxidase 4 (NOX4)
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别名
- NOX4
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背景
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Synonyms: NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD (P)H-oxidase, NOX4, RENOX
Tissue Specificity: Expressed by distal tubular cells in kidney cortex and in endothelial cells (at protein level). Widely expressed. Strongly expressed in kidney and to a lower extent in heart, adipocytes, hepatoma, endothelial cells, skeletal muscle, brain, several brain tumor cell lines and airway epithelial cells.
Background: NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases. This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
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分子量
- 65 kDa
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基因ID
- 50507
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途径
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
抗原
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