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- 抗原 See all Kallikrein 6 (KLK6) 抗体
- Kallikrein 6 (KLK6)
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抗原表位
- AA 22-244
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Kallikrein 6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 品牌
- Picoband™
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for Kallikrein 6 detection. Tested with WB, Direct ELISA in Human.
- 免疫原
- E. coli-derived human Kallikrein 6 recombinant protein (Position: L22-K244).
- Top Product
- Discover our top product KLK6 Primary Antibody
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anti-Kallikrein 6 (KLK6) (AA 17-244) antibody
KLK6 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 22-244) antibodyKLK6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 91-190) antibodyKLK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Kallikrein 6 (KLK6) (AA 217-244) antibodyKLK6 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 1-30), (N-Term) antibodyKLK6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB6114 unconjugated
anti-Kallikrein 6 (KLK6) (C-Term) antibodyKLK6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (Internal Region) antibodyVerified KLK6 适用: 人 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 74-123) antibodyKLK6 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 227-244), (C-Term) antibodyKLK6 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 126-156) antibodyKLK6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB6116 unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Kallikrein 6 (KLK6)
- 别名
- KLK6 (KLK6 产品)
- 别名
- Bssp antibody, Klk7 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, Prss9 antibody, AI849898 antibody, BSP antibody, Klk29 antibody, MSP antibody, Prss18 antibody, neurosin antibody, kallikrein related peptidase 6 antibody, kallikrein related-peptidase 6 antibody, kallikrein-6 antibody, KLK6 antibody, Klk6 antibody, LOC100716801 antibody
- 背景
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Synonyms: Kallikrein-6, Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, KLK6, PRSS18, PRSS9
Tissue Specificity: In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urine. At the tissue level, highest concentrations found in glandular tissues such as salivary glands followed by lung, colon, fallopian tube, placenta, breast, pituitary and kidney. Not detected in skin, spleen, bone, thyroid, heart, ureter, liver, muscle, endometrium, testis, pancreas, seminal vesicle, ovary, adrenals and prostate. In brain, detected in gray matter neurons (at protein level). Colocalizes with pathological inclusions such as Lewy bodies and glial cytoplasmic inclusions. Overexpressed in primary breast tumors but not expressed in metastatic tumors.
Background: KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.
- UniProt
- Q92876
- 途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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