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CD44 抗体 (AA 21-259)

This anti-CD44 antibody is a 兔 多克隆 antibody detecting CD44 in FACS, WB, IHC, ELISA, IF, IHC (fro) 和 ICC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 11+ publications.
Pubmed (11 references)
产品编号 ABIN5692819
发货至: 中国

Quick Overview for CD44 抗体 (AA 21-259) (ABIN5692819)

抗原

See all CD44 抗体
CD44

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
Discover our top product CD44 Primary Antibody

  • 抗原表位

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    AA 21-259

    原理

    Anti-CD44 Antibody Picoband®

    交叉反应 （详细）

    No cross-reactivity with other proteins.

    产品特性

    Anti-CD44 Antibody Picoband® (ABIN5692819). Tested in ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human CD44 recombinant protein (Position: Q21-H259).

    亚型

    IgG
  • anti-CD44 (CD44) antibody
    anti-CD44 (CD44) antibody

    CD44 适用: 人, 小鼠 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E2F3 unconjugated

    anti-CD44 (CD44) antibody
    anti-CD44 (CD44) antibody

    KO Validated CD44 适用: 人 WB, IF, IHC (p), IP, IHC (fro), ICC, LCI 宿主: 兔 Polyclonal unconjugated

    anti-CD44 (CD44) (AA 21-220) antibody
    anti-CD44 (CD44) (AA 21-220) antibody

    CD44 适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 6G2D2 unconjugated

    anti-CD44 (CD44) antibody
    anti-CD44 (CD44) antibody

    CD44 适用: 人 FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition 宿主: 小鼠 Monoclonal MEM-85 unconjugated

    anti-CD44 (CD44) antibody
    anti-CD44 (CD44) antibody

    CD44 适用: 人, 犬, Pig FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-263 unconjugated

    anti-CD44 (CD44) (AA 148-247) antibody
    anti-CD44 (CD44) (AA 148-247) antibody

    CD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

    anti-CD44 (CD44) (AA 36-194) antibody
    anti-CD44 (CD44) (AA 36-194) antibody

    CD44 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7F4F1 unconjugated

    anti-CD44 (CD44) (AA 1-361) antibody
    anti-CD44 (CD44) (AA 1-361) antibody

    CD44 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

    anti-CD44 (CD44) antibody
    anti-CD44 (CD44) antibody

    CD44 适用: 人, Baboon, Green Monkey FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 156-3C11 unconjugated

    anti-CD44 (CD44) (AA 35-300) antibody
    anti-CD44 (CD44) (AA 35-300) antibody

    CD44 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunocytochemistry, 0.5-1 μg/mL
    Immunofluorescence, 2 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Fagan-Solis KD, et al. Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer. Mol Cancer, 2014 Jul 2. 2. Zhang P, et al. CD44 variant, but not standard CD44 isoforms, mediate disassembly of endothelial VE-cadherin junction on metastatic melanoma cells. FEBS Lett, 2014 Dec 20.

    限制

    仅限研究用

  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Wen, Xie, Zhou, Fan, Yu, Chen, Fu, Yan, Guo, Lyu, Kuang, Chai: "The role of combining medroxyprogesterone 17-acetate with human menopausal gonadotropin in mouse ovarian follicular development." in: Scientific reports, Vol. 8, Issue 1, pp. 4439, (2018) (PubMed).

    Zhang, Yan, Liu, Li, Zhang, Pang, Hu, Zhao, Xie, Zhou, Wang, Xie: "Smad3-related miRNAs regulated oncogenic TRIB2 promoter activity to effectively suppress lung adenocarcinoma growth." in: Cell death & disease, Vol. 7, Issue 12, pp. e2528, (2017) (PubMed).

    Ding, Chang, Niu, Dai, Geng, Li, Guo, Xu: "Overexpression of transcription factor Foxa2 and Hnf1α induced rat bone mesenchymal stem cells into hepatocytes." in: Cytotechnology, Vol. 68, Issue 5, pp. 2037-47, (2016) (PubMed).

    Zhang, Shang, Hao, Zheng, Li, Liang, Cui, Liu: "Effects of human umbilical cord mesenchymal stem cell transplantation combined with minimally invasive hematoma aspiration on intracerebral hemorrhage in rats." in: American journal of translational research, Vol. 7, Issue 11, pp. 2176-86, (2016) (PubMed).

    Zhang, Wang, Dai, Cai, Zhan, Gang, Hu, Xia, Zhang: "Lentivirus-mediated PLCγ1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma." in: Oncotarget, Vol. 7, Issue 7, pp. 8043-54, (2016) (PubMed).

    Yin, Zhou, Wang, Ma, Li, Wang, She, Li: "CD44 promotes the migration of bone marrow-derived mesenchymal stem cells toward glioma." in: Oncology letters, Vol. 11, Issue 4, pp. 2353-2358, (2016) (PubMed).

    Yuan, Liu, Li, Li, Sun, Xu, Man, Fu: "Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes." in: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3957-65, (2015) (PubMed).

    Fu, Lv, Zhuang, Chen, Lv, Li, Wang: "An effective inducer of dopaminergic neuron-like differentiation." in: Neural regeneration research, Vol. 8, Issue 5, pp. 427-34, (2014) (PubMed).

    Lin, Li, Han, Li, Lu, Bai, Chen: "Folium Sennae protects against hydroxyl radical-induced DNA damage via antioxidant mechanism: an in vitro study." in: Botanical studies, Vol. 55, Issue 1, pp. 16, (2014) (PubMed).

    Dai, Li, Zhou, Chen, Chen, Xiao: "Genistein promotion of osteogenic differentiation through BMP2/SMAD5/RUNX2 signaling." in: International journal of biological sciences, Vol. 9, Issue 10, pp. 1089-98, (2013) (PubMed).

    Li, Yi, Wu: "Suspension culture combined with chemotherapeutic agents for sorting of breast cancer stem cells." in: BMC cancer, Vol. 8, pp. 135, (2008) (PubMed).

  • 抗原

    CD44

    别名

    CD44

    背景

    Synonyms: CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4

    Tissue Specificity: Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.

    Background: CD44 is also known as LHR or MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

    分子量

    82 kDa

    基因ID

    960

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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