C7 抗体 (AA 233-453)
Quick Overview for C7 抗体 (AA 233-453) (ABIN5692807)
抗原
See all C7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 233-453
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原理
- Anti-Complement C7 Antibody Picoband®
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品牌
- Picoband™
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Rabbit IgG polyclonal antibody for Complement C7 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Complement C7 recombinant protein (Position: R233-D453).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Barroso, S., Rieubland, C., Alvarez, A. J., Lopez-Trascasa, M., Bart, P.-A., Nunez-Roldan, A., Sanchez, B. Molecular defects of the C7 gene in two patients with complement C7deficiency. Immunology 118: 257-260, 2006. 2. Coto, E., Martinez-Naves, E., Dominguez, O., DiScipio, R. G., Urra, J. M., Lopez-Larrea, C.DNA polymorphism and linkage relationship of the human complement component C6,C7, and C9 genes. Immunogenetics 33: 184-187, 1991. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- C7 (Complement Component C7 (C7))
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别名
- C7
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背景
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Synonyms: Complement component C7, C7
Tissue Specificity: Widely expressed.
Background: This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.
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分子量
- 93 kDa
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基因ID
- 730
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UniProt
- P10643
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途径
- Complement System
抗原
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