LTB 抗体 (AA 31-221)
Quick Overview for LTB 抗体 (AA 31-221) (ABIN5690619)
抗原
See all LTB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 31-221
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特异性
- Recognizes mouse LTbetaR.
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纯度
- > 95% (SDS-PAGE)
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免疫原
- Recombinant mouse LTbetaR (cysteine-rich region/aa 31-221).
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亚型
- IgG2a
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anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (AA 41-90) antibody
LTB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (AA 58-304) antibodyLTB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (C-Term) antibodyLTB 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (AA 171-244) antibodyLTB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (C-Term) antibodyLTB 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) antibodyLTB 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (C-Term) antibodyLTB 适用: 人, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (C-Term) antibodyLTB 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (AA 35-84) antibodyLTB 适用: 人, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (AA 181-230) antibodyLTB 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Functional Application: Agonist inducing BAFF, chemokines and integrins in vitro and in vivo.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. In PBS containing 10 % glycerol.
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储存条件
- -20 °C
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储存方法
- Stable for at least 1 year after receipt when stored at -20°C.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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别名
- LTbeta
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背景
- The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
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基因ID
- 17000
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UniProt
- P50284
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途径
- NF-kappaB Signaling
抗原
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