LTB 抗体 (AA 181-230)
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北京 101111
Quick Overview for LTB 抗体 (AA 181-230) (ABIN1533839)
抗原
See all LTB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-230
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原理
- LT-β Antibody
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特异性
- LT-β Polyclonal Antibody detects endogenous levels of LT-β protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TNFC. AA range:181-230
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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别名
- TNFC
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背景
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Synonyms: LTB, TNFC, TNFSF3, Lymphotoxin-beta, LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3
Background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Gene Name: LTB
Protein Name: Lymphotoxin-beta
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分子量
- 25 kDa
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基因ID
- 4050
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OMIM
- 600978
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UniProt
- Q06643
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途径
- NF-kappaB Signaling
抗原
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