TRIP12 抗体 (AA 1930-1980)
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北京 101111
Quick Overview for TRIP12 抗体 (AA 1930-1980) (ABIN5690304)
抗原
See all TRIP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1930-1980
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特异性
- TRIP12 antibody is human, mouse and rat reactive. At least four isoforms are known to exist.
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纯化方法
- TRIP12 antibody is affinity chromatography purified via peptide column.
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免疫原
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TRIP12 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human TRIP12.
The immunogen is located within amino acids 1930 - 1980 of TRIP12. -
亚型
- IgG
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anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 1-240) antibody
TRIP12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 991-1023) antibodyTRIP12 适用: 人 WB 宿主: 兔 Polyclonal RB54123 unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 75-125) antibodyTRIP12 适用: 人, 犬, 豚鼠, Pig WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- TRIP12 antibody can be used for detection of TRIP12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TRIP12 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- TRIP12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))
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别名
- TRIP12
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背景
- Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner (1). TRIP12 (thyroid hormone receptor interactor 12) is an ATP-dependent E3 ubiquitin ligase involved in the human ubiquitin fusion degradation (UFD) pathway and also modulates the NEDD8 pathway (2,3). TRIP12 contains one WWE domain and a single HECT (E6AP-type E3 ubiquitin-protein ligase) domain suggested to contain a noncovalent ubiquitin-binding site (4). TRIP12 acts as a key regulator of DNA damage response and the ubiquitin ligase activity of TRIP12 is essential for mouse development (5).
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分子量
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Predicted: 219 kDa
Observed: 220 kDa -
基因ID
- 9320
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NCBI登录号
- NP_004229
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UniProt
- Q14669
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途径
- Nuclear Hormone Receptor Binding
抗原
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