TRIP12 抗体 (AA 950-1030)
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北京 101111
Quick Overview for TRIP12 抗体 (AA 950-1030) (ABIN7231912)
抗原
See all TRIP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 950-1030
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原理
- Rabbit Anti-TRIPC Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of TRIPC protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human TRIPC protein at AA range: 950-1030
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亚型
- IgG
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anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 1-240) antibody
TRIP12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 991-1023) antibodyTRIP12 适用: 人 WB 宿主: 兔 Polyclonal RB54123 unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 75-125) antibodyTRIP12 适用: 人, 犬, 豚鼠, Pig WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 75-125) antibodyTRIP12 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))
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别名
- TRIPC
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背景
- E3 ubiquitin-protein ligase TRIP12, E3 ubiquitin-protein ligase for Arf, ULF, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12TRIP12 (Thyroid Hormone Receptor Interactor 12) is a Protein Coding gene. Diseases associated with TRIP12 include Non-Syndromic Intellectual Disability and Chronic Dacryocystitis. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. The protein encoded by TRIP12 is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.
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分子量
- 219kD
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基因ID
- 9320
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UniProt
- Q14669
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途径
- Nuclear Hormone Receptor Binding
抗原
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