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NADPH Oxidase 4 抗体 (AA 70-120)

This anti-NADPH Oxidase 4 antibody is a 兔 多克隆 antibody detecting NADPH Oxidase 4 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5690084
发货至: 中国

Quick Overview for NADPH Oxidase 4 抗体 (AA 70-120) (ABIN5690084)

抗原

See all NADPH Oxidase 4 (NOX4) 抗体
NADPH Oxidase 4 (NOX4)

适用

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人, 大鼠, 小鼠

宿主

  • 94
  • 18

克隆类型

  • 84
  • 29
多克隆

标记

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This NADPH Oxidase 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
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    AA 70-120

    特异性

    NOX4 antibody is human, mouse, and rat reactive. At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins.

    纯化方法

    NOX4 antibody is affinity chromatography purified via peptide column.

    免疫原

    NOX4 antibody was raised against a 14 amino acid peptide near the amino terminus of human NOX4.

    The immunogen is located within amino acids 70 - 120 of NOX4.

    亚型

    IgG
  • 应用备注

    NOX4 antibody can be used for detection of NOX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NOX4 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    NOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    NADPH Oxidase 4 (NOX4)

    别名

    NOX4

    背景

    The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX4 is is expressed in multiple tissues and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) (2,3). Unlike other NOX proteins, NOX4 does not require cytosolic subunits and thus is constitutively active (4). The function of NOX4 remains unclear as it plays both protective and deleterious roles in cellular metabolism.

    分子量

    Predicted: 64 kDa

    Observed: 68 kDa

    基因ID

    50507

    NCBI登录号

    NP_058627

    UniProt

    Q9NPH5

    途径

    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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