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EGF 抗体 (pTyr1092)

This anti-EGF antibody is a 兔 多克隆 antibody detecting EGF in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689726
发货至: 中国

Quick Overview for EGF 抗体 (pTyr1092) (ABIN5689726)

抗原

See all EGF 抗体
EGF (Epidermal Growth Factor (EGF))

适用

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人, 小鼠, 大鼠

宿主

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  • 10
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  • 2
  • 1

克隆类型

  • 234
  • 66
多克隆

标记

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This EGF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    • 1
    pTyr1092

    特异性

    This antibody detects endogenous level of EGFR only when phosphorylated at tyrosine 1092.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

    免疫原

    EGFR (Phospho-Tyr1092) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1092 (P-E-Y (p) -I-N) derived from Human EGFR.
  • 应用备注

    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    EGF (Epidermal Growth Factor (EGF))

    别名

    EGF

    背景

    Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

    分子量

    175 kDa

    基因ID

    1956

    NCBI登录号

    NP_005219

    UniProt

    P00533

    途径

    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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