MAP2K5 抗体 (pSer311, pThr315)
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Quick Overview for MAP2K5 抗体 (pSer311, pThr315) (ABIN5689662)
抗原
See all MAP2K5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer311, pThr315
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特异性
- This antibody detects endogenous level of MEK5 only when phosphorylated at serine 311 or threonine 315.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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免疫原
- MEK5 (phospho-Ser311/ Thr315) antibody was raised against a peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S (p) I-A-K-T (p) -Y-V) derived from Rat MEK5.
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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别名
- MEK5
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背景
- Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
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分子量
- 46 kDa
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基因ID
- 29568
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NCBI登录号
- NP_001029159
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UniProt
- Q62862
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway
抗原
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