Src 抗体 (AA 527-531)
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Quick Overview for Src 抗体 (AA 527-531) (ABIN5689590)
抗原
See all Src 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 527-531
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特异性
- This antibody detects endogenous level of total Src protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- Src (Ab-529) antibody was raised against a peptide sequence around aa. 527~531 (P-Q-Y-Q-P) derived from Human Src.
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应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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别名
- Src
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背景
- Proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme, phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
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分子量
- 60 kDa
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基因ID
- 6714
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NCBI登录号
- NP_005408
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UniProt
- P12931
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途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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