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PRKDC 抗体 (AA 2607-2611)
This anti-PRKDC antibody is a 兔 多克隆 antibody detecting PRKDC in WB. Suitable for 人.
Quick Overview for PRKDC 抗体 (AA 2607-2611) (ABIN5689450)
抗原
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PRKDC
(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
适用
All reactivities for PRKDC 抗体
人
宿主
All hosts for PRKDC 抗体
兔
克隆类型
All clonalities for PRKDC 抗体
多克隆
标记
All conjugates for PRKDC 抗体
This PRKDC antibody is un-conjugated
应用范围
All applications for PRKDC 抗体
Western Blotting (WB)
PRKDC抗体详情
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抗原表位
All epitopes for PRKDC 抗体
AA 2607-2611
特异性
This antibody detects endogenous level of total DNA PKcs protein.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
DNA PKcs (Ab-2609) antibody was raised against a peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK.
Alternatives
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使用细节
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应用备注
Western Blot: 1:500~1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
PRKDC目标详情
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抗原
PRKDC
(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
别名
DNA PKcs
背景
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity, PRKDC must be bound to DNA to express its catalytic properties
分子量
450 kDa
基因ID
5591
NCBI登录号
NP_001075109
UniProt
P78527
途径
DNA Damage Repair , Production of Molecular Mediator of Immune Response
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原发性抗体
anti-PRKDC 抗体 (AA 2607-2611) (ABIN5689450)
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