PRKDC 抗体 (AA 2607-2611)
Our Local Distributor
北京 101111
Quick Overview for PRKDC 抗体 (AA 2607-2611) (ABIN5689450)
抗原
See all PRKDC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2607-2611
-
特异性
- This antibody detects endogenous level of total DNA PKcs protein.
-
纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
免疫原
- DNA PKcs (Ab-2609) antibody was raised against a peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK.
-
-
-
-
应用备注
- Western Blot: 1:500~1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store antibody at -20°C for up to one year.
-
-
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
-
别名
- DNA PKcs
-
背景
- The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity, PRKDC must be bound to DNA to express its catalytic properties
-
分子量
- 450 kDa
-
基因ID
- 5591
-
NCBI登录号
- NP_001075109
-
UniProt
- P78527
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-