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TFE3 抗体 (AA 303-307)

This anti-TFE3 antibody is a 兔 多克隆 antibody detecting TFE3 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN5689356
发货至: 中国

Quick Overview for TFE3 抗体 (AA 303-307) (ABIN5689356)

抗原

See all TFE3 抗体
TFE3 (Transcription Factor E3 (TFE3))

适用

  • 62
  • 37
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  • 1
人, 小鼠

宿主

  • 58
  • 2
  • 1
  • 1

克隆类型

  • 59
  • 3
多克隆

标记

  • 41
  • 4
  • 4
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  • 2
  • 2
  • 1
  • 1
  • 1
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This TFE3 antibody is un-conjugated

应用范围

  • 45
  • 30
  • 14
  • 8
  • 8
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 9
    • 8
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    • 2
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    • 1
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    • 1
    • 1
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    • 1
    AA 303-307

    特异性

    This antibody detects endogenous levels of total TFE3 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    TFE3 antibody was raised against a peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    TFE3 (Transcription Factor E3 (TFE3))

    别名

    TFE3

    背景

    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

    分子量

    70 kDa

    基因ID

    7030

    NCBI登录号

    NP_006512

    UniProt

    P19532
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