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PKC theta 抗体 (AA 674-678)

This 兔 多克隆 anti-PKC theta antibody specifically detects PKC theta in WB, IHC 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN5689324
发货至: 中国
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Quick Overview for PKC theta 抗体 (AA 674-678) (ABIN5689324)

抗原

See all PKC theta (PRKCQ) 抗体
PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 123
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多克隆

标记

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This PKC theta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 674-678

    特异性

    This antibody detects endogenous level of total PKCΘ, protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    PKCtheta (Ab-676) antibody was raised against a peptide sequence around aa. 674~678 (R-L-S-F-A) derived from Human PKCΘ,.
  • 应用备注

    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

    别名

    PKCtheta

    背景

    This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-κ,-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

    分子量

    80 kDa

    基因ID

    5588

    NCBI登录号

    NP_006248

    UniProt

    Q04759

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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