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JUP 抗体 (AA 726-730)

This anti-JUP antibody is a 兔 多克隆 antibody detecting JUP in WB. Suitable for 人 和 大鼠.
产品编号 ABIN5689306
发货至: 中国

Quick Overview for JUP 抗体 (AA 726-730) (ABIN5689306)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

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人, 大鼠

宿主

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  • 1

克隆类型

  • 93
  • 82
多克隆

标记

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This JUP antibody is un-conjugated

应用范围

  • 113
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  • 18
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Western Blotting (WB)
  • 抗原表位

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    AA 726-730

    特异性

    This antibody detects endogenous levels of total gamma-Catenin protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    gamma-Catenin antibody was raised in was raised against a peptide sequence around aa.726~730 (I-D-T-Y-S) derived from Human gamma-Catenin.
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    gamma Catenin 

    背景

    Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton

    分子量

    83 kDa

    基因ID

    3728

    NCBI登录号

    NP_002221

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
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