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E2F1 抗体 (AA 430-434)

This anti-E2F1 antibody is a 兔 多克隆 antibody detecting E2F1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN5689264
发货至: 中国

Quick Overview for E2F1 抗体 (AA 430-434) (ABIN5689264)

抗原

See all E2F1 抗体
E2F1 (E2F Transcription Factor 1 (E2F1))

适用

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人, 小鼠

宿主

  • 206
  • 13
  • 2

克隆类型

  • 193
  • 28
多克隆

标记

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This E2F1 antibody is un-conjugated

应用范围

  • 186
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  • 28
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Western Blotting (WB)
  • 抗原表位

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    • 1
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    • 1
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    AA 430-434

    特异性

    This antibody detects endogenous levels of total E2F-1 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    E2F-1 antibody  was raised against a peptide sequence around aa.430~434 (G-D-L-T-P) derived from Human E2F-1.
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    E2F1 (E2F Transcription Factor 1 (E2F1))

    别名

    E2F 1 

    背景

    Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis.

    分子量

    70 kDa

    基因ID

    1869

    NCBI登录号

    NP_005216

    UniProt

    Q01094

    途径

    p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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