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MAP2K5 抗体 (AA 311-315)

This anti-MAP2K5 antibody is a 兔 多克隆 antibody detecting MAP2K5 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689204
发货至: 中国

Quick Overview for MAP2K5 抗体 (AA 311-315) (ABIN5689204)

抗原

See all MAP2K5 抗体
MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

适用

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人, 小鼠, 大鼠

宿主

  • 139
  • 7

克隆类型

  • 132
  • 14
多克隆

标记

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This MAP2K5 antibody is un-conjugated

应用范围

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  • 3
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Western Blotting (WB)
  • 抗原表位

    • 29
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    • 16
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    • 1
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    • 1
    AA 311-315

    特异性

    This antibody detects endogenous level of total MEK5 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide

    免疫原

    MEK5 antibody was raised against a peptide sequence around aa. 311-315 (K-T-Y-V-G ) derived from Rat MEK5.
  • 应用备注

    Western Blot: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

    别名

    MEK5

    背景

    A family of protein kinases located upstream of the MAP kinases andresponsible for their activation has been identified. The prototype member ofthis family, designated MAP kinase kinase, or MEK-1, specifically phospho-rylates the MAP kinase regulatory threonine and tyrosine residues present inthe Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resem-bles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to acti-vate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activatesboth p38 and JNK MAP kinases. MEK-5 appears to specifically phosphory-late ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7)phosphorylates and activates the JNK signal transduction pathway.

    分子量

    49 kDa

    基因ID

    29568

    NCBI登录号

    NP_001029159

    UniProt

    Q62862

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway
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