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SYN1 抗体 (pSer549)

This anti-SYN1 antibody is a 兔 多克隆 antibody detecting SYN1 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow 和 犬.
产品编号 ABIN5688905
发货至: 中国

Quick Overview for SYN1 抗体 (pSer549) (ABIN5688905)

抗原

See all SYN1 抗体
SYN1 (Synapsin I (SYN1))

适用

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  • 92
  • 69
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  • 1
  • 1
人, 大鼠, 小鼠, Cow, 犬

宿主

  • 126
  • 8

克隆类型

  • 117
  • 17
多克隆

标记

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This SYN1 antibody is un-conjugated

应用范围

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  • 7
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer549

    纯化方法

    Affinity Purified

    免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser549 of synapsin I.
  • 应用备注

    The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, non-human primate, bovine and canine tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    Synapsin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原

    SYN1 (Synapsin I (SYN1))

    别名

    Synapsin

    背景

    Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.

    分子量

    78 kDa

    基因ID

    281510

    UniProt

    P17599
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