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CD42b 抗体 (AA 17-183)

This anti-CD42b antibody is a 小鼠 单克隆 antibody detecting CD42b in FACS, WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN5684109
发货至: 中国

Quick Overview for CD42b 抗体 (AA 17-183) (ABIN5684109)

抗原

See all CD42b (GP1BA) 抗体
CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD42b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

6H6H10
  • 抗原表位

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    AA 17-183

    原理

    CD42B Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD42B (AA: 17-183) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

    别名

    CD42B

    背景

    Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

    分子量

    71.5 kDa

    基因ID

    2811
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