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FLT4 抗体

FLT4 适用: 小鼠 WB 宿主: 大鼠 Monoclonal 7A3 unconjugated
产品编号 ABIN567980
发货至: 中国
  • 抗原 See all FLT4 抗体
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    适用
    • 73
    • 45
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    小鼠
    宿主
    • 67
    • 21
    • 2
    • 2
    大鼠
    克隆类型
    • 68
    • 24
    单克隆
    标记
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    This FLT4 antibody is un-conjugated
    应用范围
    • 51
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    Western Blotting (WB)
    特异性
    This antibody will detect VEGFR-3/FLT-4 in WB in PAEC/FLT-4 cells.
    纯化方法
    Protein G Chromatography
    免疫原
    Purified, insect cell-derived recombinant Mouse soluble FLT-4 (120 kDa).
    克隆位点
    7A3
    亚型
    IgG1
    Top Product
    Discover our top product FLT4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS pH 7.4 without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    别名
    VEGFR-3 / Flt-4 (FLT4 产品)
    别名
    FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
    背景
    Mature native mouse VEGF Receptor 3 (Flt4) is composed of a 751 amino acid residue extracellular domain, a 22 amino acid residue transmembrane domain, and a 565 amino acid residue cytoplasmic domain. Recombinant mature mouse VEGF Receptor 3/Fc is a disulfidelinked dimeric protein. Based on N-terminal sequencing, recombinant mouse VEGF Receptor 3/Fc has Met 17 at the amino-terminus. The amino acid sequence of mouse VEGF Receptor 3 is 88 % identical to human VEGF Receptor 3. VEGF Receptor 3 is a specific marker for lymphatic vessels. In adults, VEGF Receptor 3 expression is restricted to endothelial cells of the lymphatic vessels. It has also been detected on some high endothelial venules, in embryonic prelymphatic blood vessels, in some tumor blood vessels, and in certain hematopoietic and leukemia cells. The predominant role of VEGF Receptor 3 is its involvement in the development of the lymphatic vessel system. Both VEGFC and VEGFD bind and activate the receptors, VEGF Receptor 3 and VEGF Receptor 2.Synonyms: FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3
    基因ID
    14257
    NCBI登录号
    NP_032055
    UniProt
    P35917
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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