Cyclin E1 抗体
Quick Overview for Cyclin E1 抗体 (ABIN567783)
抗原
See all Cyclin E1 (CCNE1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Cyclin E (50 kDa) on Western blotting. This monoclonal antibody may nonspecifically react with macrophages, endothelial cells and some stromal cells in Immunohistochemistry.
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纯化方法
- Protein-A Agarose Chromatography of hybridoma supernatant.
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免疫原
- Human recombinant full length His-Cyclin E.
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亚型
- IgG1
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anti-Cyclin E1 (CCNE1) (AA 10-176) antibody
CCNE1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CCNE1-2460 unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-100) antibodyCCNE1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1C8D4 unconjugated
anti-Cyclin E1 (CCNE1) (AA 307-410) antibodyCCNE1 适用: 人, 小鼠 ELISA, FACS 宿主: 小鼠 Monoclonal 5F8C5 unconjugated
anti-Cyclin E1 (CCNE1) (AA 375-411) antibodyCCNE1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 307-410) antibodyCCNE1 适用: 人, 小鼠 宿主: 小鼠 Monoclonal unconjugated
anti-Cyclin E1 (CCNE1) (Thr395) antibodyCCNE1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) antibodyCCNE1 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 3A5 unconjugated Recombinant Antibody
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (C-Term) antibodyCCNE1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- Cyclin E1 (CCNE1)
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别名
- Cyclin E1
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背景
- Cyclin E, a positive regulator of the cell cycle, controls the transition of cells from G1 to S phase. Cyclin E forms a complex with Cdk2, the active kinase follows cyclin D/Cdk4 in progressively phosphorylating pRb, releasing it from members of the E2F family. E2F transcrIPPtion factors in turn activate a set of target genes that are essential for entry into S phase. Deregulation of the G1-S checkpoint contributes to uncontrolled cell division, a hallmark of cancer. Cyclin E overexpression and deregulation have been shown in several cancers including breast, colorectal, gastric and lungSynonyms: CCNE, CCNE1, Cyclin-E1
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基因ID
- 898
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NCBI登录号
- NP_001229
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UniProt
- P24864
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途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
抗原
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