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SMAD2 抗体 (pSer250) (Biotin)

This anti-SMAD2 antibody is a 兔 多克隆 antibody detecting SMAD2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN5675085
发货至: 中国

Quick Overview for SMAD2 抗体 (pSer250) (Biotin) (ABIN5675085)

抗原

See all SMAD2 抗体
SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SMAD2 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA
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    pSer250

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthesised phosphopeptide derived from human Smad2 around the phosphorylation site of Ser250

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

    别名

    Smad2

    背景

    Synonyms: Smad2 (phospho S250), p-Smad2 (phospho S250), hMAD 2, hMAD 3, hSMAD2, hSMAD3, Mad related protein 2, MADH2, MADH3, MADR2, Mothers against DPP homolog 2, Mothers against DPP homolog 3, Sma and Mad related protein 2, SMA and MAD related protein 3, SMAD 2, SMAD 3, SMAD family member 2, SMAD family member 3.

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.

    基因ID

    4087

    UniProt

    Q15796

    途径

    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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