FASL 抗体 (N-Term)
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Quick Overview for FASL 抗体 (N-Term) (ABIN5672079)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- APPGTVLPCP TSVPRRPGQR RPPPPPPPPP LPPPPPPPPL PPLPLPPLKK
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FASLG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- FASLG
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背景
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This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Alias Symbols: APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1
Protein Size: 281 -
基因ID
- 356
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NCBI登录号
- NM_000639, NP_000630
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UniProt
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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