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Recombinant CD40 抗体

This 兔 Chimeric antibody specifically detects CD40 in FACS, IHC, IP 和 Act. It exhibits reactivity toward 人.
产品编号 ABIN5668238
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant CD40 抗体 (ABIN5668238)

抗原

See all CD40 抗体
CD40

抗体类型

Recombinant Antibody

适用

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克隆类型

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Chimeric

标记

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This CD40 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Activation (Act)

克隆位点

G28-5
  • 原理

    Anti-CD40 [G28.5], Rabbit IgG, kappa

    特异性

    48 kD Type I glycoprotein, a member of the TNFR superfamily primarily expressed on normal or malignant B cells or B cell lines, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    Human erythrocyte-rosette-negative tonsillar lymphocytes.

    亚型

    IgG kappa
  • 应用备注

    This antibody detects CD40 by immunostaining. The original mouse IgG1 format was shown to stimulate B-cells (Bishop 2012 and references therein).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD40

    别名

    CD40

    背景

    TNFRS5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor CDw40, CD154R

    UniProt

    P25942

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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