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Recombinant CD3 epsilon 抗体

This anti-CD3 epsilon antibody is a 兔 Chimeric antibody detecting CD3 epsilon in FACS 和 Act. Suitable for 人.
产品编号 ABIN5668185
发货至: 中国

Quick Overview for Recombinant CD3 epsilon 抗体 (ABIN5668185)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

抗体类型

Recombinant Antibody

适用

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克隆类型

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Chimeric

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Activation (Act)

克隆位点

12F6
  • 原理

    Anti-CD3 epsilon [12F6], Rabbit IgG, kappa

    特异性

    This antibody binds to human CD3.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    Human CD3

    亚型

    IgG kappa
  • 应用备注

    This antibody competes for CD3 binding with the therapeutic antibody OKT3 (Ab00122). 12F6 binding to CD3 on human T-cells stimulates the secretion of TNF-alpha, INF-gamma and IL-10. Humanized versions of this antibody are also available.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3 epsilon

    背景

    Leu4/T3, ET-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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