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CD42a 抗体 (PE)

This anti-CD42a antibody is a 小鼠 单克隆 antibody detecting CD42a in FACS. Suitable for 人 和 犬.
产品编号 ABIN5665750
发货至: 中国

Quick Overview for CD42a 抗体 (PE) (ABIN5665750)

抗原

See all CD42a (GP9) 抗体
CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

适用

  • 67
  • 12
  • 9
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
人, 犬

宿主

  • 43
  • 30
小鼠

克隆类型

  • 44
  • 28
  • 1
单克隆

标记

  • 42
  • 9
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD42a antibody is conjugated to PE

应用范围

  • 37
  • 28
  • 23
  • 19
  • 17
  • 16
  • 11
  • 2
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

GR-P
  • 原理

    Anti-Hu CD42a PE

    特异性

    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.

    交叉反应 (详细)

    Human, Canine (Dog)

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human acute lymphoblastic leukemia cells

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

    别名

    CD42a

    背景

    Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9

    基因ID

    2815

    UniProt

    P14770
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